According to Louvre Curator Jean-Pierre Cuzin, "The entire history of portraiture afterwards depends on the Mona Lisa. If you look at all the other portraits – not only of the Italian Renaissance, but also of the seventeenth to nineteenth centuries – if you look at Picasso, at everyone you want to name, all of them were inspired by this painting. Thus it is sort of the root, almost, of occidental portrait painting."
Pixel, Web3, Crypto Art and Renaissance.